Natural products chemistry services
Our natural products chemistry team have long-standing expertise in the isolation and identification of bioactive compounds from sources such as dairy, plants, bees and fish.
Our services
Chemical analysis
- HPLC with UV, MS and ELSD detection
- UV-Vis spectroscopy
- LCMS/MS and high-resolution MS
- UPC2 analytical supercritical-fluid HPLC with MS/UV or ELSD
- NMR spectroscopy
Chemical separations
- Benchtop column chromatography
- Preparative HPLC (mg to multi gram quantities)
- Lab scale separations, using resin columns for example, to test process method prior to scale-up
Extract preparation
- Solvent extractions
- Freeze drying
- Centrifugal vacuum drying
- Automated solvent extraction
- Preparation of complexes (eg cyclodextrin complexes of natural products)
- Shear mixing, microfluidising
- Centrifugation
- Vacuum drying
Preparation and analysis of metabolites
- Analysis of drug/natural product metabolites in plasma (using LCMS)
- Synthesis of metabolites using enzymatic methods eg glucuronides of drug type compounds
- Synthesis of metabolites using chemical synthesis eg sulphates of drug type compounds
Knowledge of natural products
- Assist customers with literature searches
- Provide advice on natural products chemistry, extraction and analysis